← brief for 2026-08-10 · People & money

A novel TRPC6 variant (c.131C>T, p.(Pro44Leu)) associated with focal segmental glomerulosclerosis: a case report

Key takeaways

This report describes one patient with a newly found gene change (in a gene called TRPC6) linked to a kidney-scarring disease called FSGS. A single case cannot prove the gene causes the disease, but it adds to what is known.

Who did this work

Fan Yang (Beijing Luhe Hospital Affiliated to Capital Medical University) · Xiaoqi Wang (Beijing Luhe Hospital Affiliated to Capital Medical University) · Yan Li (Beijing Luhe Hospital Affiliated to Capital Medical University) · K. Su (Beijing Luhe Hospital Affiliated to Capital Medical University) · Ran Ding (Beijing Luhe Hospital Affiliated to Capital Medical University) · Linlin Wu (Beijing Luhe Hospital Affiliated to Capital Medical University) · Guorong Ma (Beijing Luhe Hospital Affiliated to Capital Medical University) · Jianjie Yang (Beijing Luhe Hospital Affiliated to Capital Medical University) · Zhongxin Li (Beijing Luhe Hospital Affiliated to Capital Medical University)

Source

Indexed paper · OpenAlex — CKD concept sweep (DB seed + weekly delta) · 2026-08-10
https://doi.org/10.3389/fgene.2026.1913168