← brief for 2026-08-10 · Slowing decline

Glomerular-Targeted Delivery of Low-Dose Prednisolone Attenuates Established Lupus Nephritis in MRL/lpr Mice.

Key takeaways

In mice, delivering a low dose of a steroid (prednisolone) aimed straight at the kidney's filters eased lupus-related kidney damage. This is an animal study, not tested in people yet.

Who did this work

Kristof Williams (University of South Florida) · Georgina Agyekum (University of South Florida) · Akshata Patne (University of South Florida) · Eleni Markoutsa (University of South Florida) · David Raj Chellappan (University of South Florida) · Nathan Hall (University of South Florida) · Zhi Tian (University of South Florida) · Nohely Hernandez Soto (University of South Florida) · Sebastian Cuadrao (University of South Florida) · Isabella Lozonschi (University of South Florida) · Liying Fu (Mayo Clinic in Arizona) · Lilliana Haight (University of South Florida)

Source

Indexed paper · OpenAlex — CKD concept sweep (DB seed + weekly delta) · 2026-08-06
https://doi.org/10.64898/2026.08.01.742194