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Effect of semaglutide on kidney outcomes in the SELECT, FLOW, and SOUL trials: a prespecified pooled analysis.

Article A Peer reviewed Meta-analysis or large trial

Key takeaways

This pooled three large trials — called SELECT, FLOW, and SOUL — to measure how the drug semaglutide affects the kidneys. It checked whether semaglutide protects kidney health over time. Pooling big trials like this gives strong evidence.

Who did this work

Mann JFE · Badve SV · Baeres FMM · Belmar N · Brown-Frandsen K · Buse JB · Colhoun HM · Deanfield JE · Engelmann MDM · Hovingh GK · Idorn T · Lincoff AM

Source

Journal article · PubMed — the drug frontier · 2026 Aug 7
https://pubmed.ncbi.nlm.nih.gov/42567173/