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Systems pharmacology, structural modeling, and experimental validation reveal retinoic acid as a modulator of immune-fibrotic networks in chronic kidney disease

Paper B Peer reviewed Small trial

Key takeaways

This study using human kidney organoids found that retinoic acid can modulate fibrotic networks. It may help prevent fibrosis (scarring) in CKD patients.

Who did this work

Ayman E. Abdelaziz · Ahmed A. Shokeir · Basem I. Awad · Omali Y. El‐khawaga

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-08-15
https://doi.org/10.1007/s00210-026-05782-z