← brief for 2026-08-19 · Slowing decline

Real-world effectiveness of SGLT2 inhibitors in adults aged 75 years or older: a target trial emulation.

Article B Peer reviewed Small trial

Key takeaways

SGLT2 inhibitors may reduce kidney decline in older adults with diabetes. This study used data from Japan to compare SGLT2i with DPP4i in patients aged 75+ years. The results could change how we treat older diabetics.

Who did this work

Noma H · Goto A · Sugimoto T · Sunada H · Oda F · Maeda M · Fukuda H

Source

Article · PubMed, the drug frontier · 2026 Aug 3
https://pubmed.ncbi.nlm.nih.gov/42613674/