← brief for 2026-09-10 · Nutrition & lifestyle

Shenshuai Yingyang Jiaonang attenuates CKD-induced muscle atrophy: a role for Faecalibacterium prausnitzii and the EGFR/PI3K/AKT signaling axis.

Article D Peer reviewed Preclinical

Key takeaways

Muscle wasting is common in kidney disease and there is no good treatment for it. This study tested a traditional Chinese herbal formula, Shenshuai Yingyang Jiaonang, in animals with kidney disease and found it reduced muscle loss. The effect ran through a shift in gut bacteria, especially one called Faecalibacterium prausnitzii, and a chain of growth signals inside muscle cells. This was in animals and cells, not people, so it is an early lead and not something to take.

Who did this work

He Z · He J · Zhang C · Wang H · Wang F · Pei T · Hu R · Xian Z · Li J · Liu D · Shi C · Yu C

Source

Article · PubMed, Nutritional supplements and CKD · 2026 Sep 3
https://pubmed.ncbi.nlm.nih.gov/42721824/