← brief for 2026-09-16 · Slowing decline

Pharmacological antagonism of HTR2B reduces ERK and STAT3 activation and prevents renal fibrosis during the development of Adenine-Induced CKD in rats.

Key takeaways

A drug blocked a receptor in rats and reduced scarring and loss of kidney function after feeding them adenine, but this was an animal study and has not been tested in people yet.

Who did this work

McAlister KW · Scholpa NE · Janda J · Schnellmann RG

Source

Article · PubMed, CKD progression and prevention · 2026 Sep 16
https://pubmed.ncbi.nlm.nih.gov/42749227/