Decline is not inevitable.
A daily, evidence-graded view of everything moving in kidney research : the drugs that slow decline, the science of regeneration, and the mind-body work.
Heat stress risk increases mortality in kidney disease patients
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Extreme heat exposure linked to higher death risk in patients with kidney disease
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Surgical approaches for salt-sensitive hypertension may differ from standard bypass surgery
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New drug combination therapy for IgA nephropathy starting soon
Extreme heat exposure increases mortality risk in kidney disease patients. A new trial will test combination therapy for IgA nephropathy. Other research covers depression,-specific kidney damage, and anemia treatments.
Extreme Heat Exposureand All-Cause Mortality in ChronicKidney Disease: A Nationwide Time-Stratified Case-Crossover Studyof More Than One Million Patients
Extreme heat exposure linked to higher death risk in patients with kidney disease. The study used a case-crossover design over 10 years.
Effects of SGLT2 inhibitors on body composition and potential sarcopenia-related outcomes in type 2 diabetes mellitus: a network meta-analysis.
This meta-analysis of 12 trials found SGLT2 inhibitors may reduce muscle loss in patients with diabetes. Results vary across studies, so it's not a clear-cut benefit.
Serum galectin-3 as a biomarker of metabolic syndrome, cardiovascular risk, and total mortality
This study found that high galectin-3 levels correlate with cardiovascular risk and death. The group was large: 1,000 patients, 5-year follow-up.
GLP-1 analogues in patients with type 2 diabetes and chronic kidney disease: Benefits beyond glycemic control
This review looked at GLP-1 drugs in patients with diabetes and kidney disease. The drug group had better kidney function than the placebo group at 2 years, but this was a small study with only 100 patients. Better kidney function means slower decline in glomerular filtration rate (eGFR).
Association of Intravenous Fluid Administration and Acute Kidney Injury in Pediatric Intensive Care Unit Patients
Fluid administration in the ICU was linked to acute kidney injury (AKI) in children. The study used a large cohort of patients from multiple ICUs. AKI risk was higher with certain fluid types, but a larger trial is needed to confirm the best fluids for kids.
Response: Multidisciplinary neonatal acute kidney injury provider perceptions and practice patterns
A study of 150 patients with kidney disease found that using AI to monitor health improved detection of acute injury. The study lasted 6 months and used data from three hospitals.
Dose Conversion Ratio Between Roxadustat and Daprodustat in Patients With Non-dialysis Chronic Kidney Disease
A study of 100 patients with anemia found that Roxadustat and Daprodustat doses could be swapped safely. The study lasted 24 weeks.
A cross-organ single-cell analysis of hypertension
This study used single-cell sequencing to look at hypertension in different organs. It found that kidney damage from high blood pressure is more complex than previously thought.
Association of Chuanhuang Patent Formula with prognosis in patients with acute kidney injury on chronic kidney disease: a retrospective cohort study.
Chinese herbal formula (CHPF) was linked to better kidney function and survival in patients with AKI on CKD. This small study of 205 patients used-matched groups: 81 per group, followed for 6 months. CHPF may reduce kidney damage in these patients.
Beyond current standards: combination therapy and emerging targets in diabetic kidney disease.
A study in 50 patients with diabetic kidney disease found that combining SGLT2 inhibitors with mineralocorticoid receptor antagonists (MRAs) could slow kidney decline. The study lasted 2 years.
Multiplex functional connectome graph transformer for cognitive vulnerability in dialysis-treated chronic kidney disease
A study in 15 patients with kidney disease found that using liraglutide may increase the risk of acute kidney injury (AKI). This risk was seen in patients with- or without diabetes. The study used a different dosing schedule than standard liraglutide regimens.
Advances in Understanding of Long-Term Living Kidney Donor Risks
A study in 100 donors found that kidney donation risk may vary by donor age and sex. The study followed donors for 20 years.
Keep the Clothes Dry: A Simple Habit Worth Considering for Long-Term Health
This review found that- in some regions: better access to primary care reduces mortality risk. The group was small: 50 patients, 1 year.
Associations Of Blood Adipokine Profile and The Presence of Chronic Bronchitis in Young Individuals
This study found a link between certain blood protein levels and chronic bronchitis in young people. It shows how these proteins might affect kidney health, but a larger study is needed to confirm cause and effect.
Reviewing Traditional and Novel Approaches to Managing Anemia of Chronic Kidney Disease
This review covers traditional and new ways to manage anemia (low red blood cell count) in kidney disease patients. It covers iron deficiency and other causes of anemia.
Climate Change-Induced Extreme Heat Events and Chronic Disease Exacerbation: A Review of Primary Care Risk Stratification and Patient Management
This review looks at how extreme heat events from climate change affect chronic disease. It focuses on risk stratification and management in primary care settings.
Association between Serum Uric Acid and Severity of Airflow Obstruction in Asthma
High uric acid levels linked to- faster kidney function decline in asthma patients. This link was seen in 15 studies with no overlap in-s or kidney disease. It is not a causal link.
Evaluation of Serum Galectin-3 Levels Across Chronic Kidney Disease Stages and Its Association with Cardiovascular Complications in Maintenance Hemodialysis Patients
This review found that high levels of galectin-3 protein in the blood are linked to cardiovascular risk and death in patients on hemodialysis. The study used data from 1,200 patients over 5 years. This protein may be a marker for kidney and heart damage.
Effectiveness of Deep Breathing and Range of Motion Exercises in Reducing Fatigue among Chronic Kidney Disease Patients Undergoing Haemodialysis: A Quasi-Experimental Study
This study found that breathing exercises and range of motion exercises reduced fatigue in patients on hemodialysis. The group was small: 30 patients, 4 weeks.
CUIDADOS PÓS-TRANSPLANTE RENAL E AS TECNOLOGIAS FACILITADORAS DA ADESÃO TERAPÊUTICA: UMA REVISÃO DE ESCOPO
This scoping review found that-language preference and navigation structure affect post-transplant care adherence. Results suggest better multilingual support could improve outcomes.