← brief for 2026-08-11 · Slowing decline

Dapagliflozin preserves kidney function and reduces albuminuria in children with chronic kidney disease

Key takeaways

A study gave dapagliflozin, a diabetes pill that also protects kidneys, to children with chronic kidney disease. The children kept more of their kidney filtering power and had less protein leaking into their urine, a key sign of kidney damage. This adds early evidence in children to the strong adult trials already showing these drugs slow kidney decline.

Who did this work

Farahnak Assadi (Rush University Medical Center) · Elham Bidabadi (Guilan University of Medical Sciences) · Mojgan Mazaheri (Milad Hospital) · Fatemeh Ghane-Sharbaf (Mashhad University of Medical Sciences) · Toktam Faghihi (Tehran University of Medical Sciences) · Rama Naghshizadian (Kurdistan University of Medical Sciences) · Alireza Eskandarifar (Kurdistan University of Medical Sciences) · Anoush Azarfar (Mashhad University of Medical Sciences) · Simin Sadeghi-Bojd (Zahedan University of Medical Sciences) · Arash Abbasi (Children's Medical Center) · Behnaz Bazargani (Children's Medical Center) · Afshin Safaei-asl (Guilan University of Medical Sciences)

Source

Paper · OpenAlex, CKD concept sweep (DB seed + weekly delta) · 2026-08-06
https://doi.org/10.1093/ndt/gfag177