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A nanoluciferase-expressing attenuated CHIKV vaccine strain enables rapid and visual drug screening in vitro and in vivo.

Key takeaways

This study uses two-cell culture models to test antiviral drugs against a virus that causes hemorrhagic fever. It focuses on how the virus replicates in endothelial cells.

Who did this work

Zheng M · Pan Z · Jiang Y · Guo Y · Chang W · Tang H · Chen X · Xiang Y · Wang X · Wang Z · Chang R · Liu L

Source

Article · PubMed, Climate, heat and the kidney · 2026 Aug 11
https://pubmed.ncbi.nlm.nih.gov/42578665/