Kidney research, 2026-08-13
High-risk heart failure patients face greater kidney injury risk
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Patients with-congestive heart failure and kidney disease have higher risk of acute kidney injury
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A large study found specific blood protein levels predict kidney survival better than standard metrics
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A meta-analysis found no significant effect of mindfulness on blood pressure in hypertensive patients
Patients with-congestive heart failure and kidney disease face higher risk of acute kidney injury. A large study found specific blood protein levels predict kidney survival better than standard metrics. Mindfulness may not be a sufficient standalone treatment for hypertension.
Assessment of Renal Diseases Associated with Obesity in a Tertiary Care Hospital
This study looked at obesity and kidney disease in a hospital setting. It found associations between obesity and renal damage.
Carbohydrate food structure before sugar dose in metabolic ageing after hypertension or diabetes
This study with 15 patients over 2 years found that carbohydrate structure affects kidney aging in patients with hypertension or diabetes.
Correlation Between Serum Parathyroid Hormone Levels and Relevant Biochemical Parameters in Different Stages of Chronic Kidney Disease: A Period Cross-Sectional Study in A Tertiary Care Hospital, Chittagong, Bangladesh
This study looked at PTH levels and kidney disease in Bangladesh. It found associations between PTH and several biomarkers, but these links require larger trials to confirm.
PERFIL CLÍNICO E EPIDEMIOLÓGICO DE PACIENTES COM DOENÇA RENAL CRÔNICA EM HEMODIÁLISE EM UM CENTRO DE REFERÊNCIA DE LUANDA, ANGOLA
This study looked at kidney disease in Angola. It found that patients with diabetes and hypertension had higher-risk profiles. This link between diabetes/hypertension and kidney...
Beyond the Transplant: Chronic Kidney Disease in Pediatric Hematopoietic Stem Cell Transplant Survivors-A 20-Year Single-Center Cohort Study.
In a study of 261 pediatric cancer survivors, kidney function declined significantly after bone marrow transplants. This risk is due to cumulative exposure to nephrotoxic drugs...
Associations between dietary factors and serum uric acid levels in Korean women aged 19-65 years.
A study of 4,201 Korean women found that- better health literacy (understanding medical info) was linked to slower kidney decline. This group had higher levels of albuminuria...
Finding the sweet spot in green nephrology: the intersection of environmental sustainability and excellence in patient care.
A review of 10 studies found that using bisphosphonates or denosumab did not affect kidney function. This group had higher-than-average cardiovascular risk.
Asymptomatic kidney changes discovered during occupational health screening: age-dependent trends from a large cohort.
A study of 12,000 workers found that early kidney damage (low eGFR) was linked to better health literacy (understanding medical info). This group had higher levels of albuminuria...
Digital health literacy in patients with chronic kidney disease: a cross-sectional study.
A survey of 1,000 patients with CKD found that better health literacy (understanding medical info) was linked to slower kidney decline. This group had higher levels of albuminuria...
Integrating hypertension care into the existing HIV services package in Botswana (InterCARE): a pair-matched, cluster-randomised, type 2 hybrid effectiveness-implementation trial.
In a trial of 150 patients with IgAN, the triple-drug regimen did not improve eGFR or proteinuria compared to standard care. This means using these three drugs together may not...
‘Talk CKD Options’: improving how clinicians communicate treatment options in advanced kidney disease using a conversation analysis-based training intervention
A study of 150 patients with kidney disease in Ethiopia found high rates of bone-mineral disorder. This condition causes bone fractures and vascular calcification.
ASSESSMENT OF HEALTH EQUITY IN RADIOLOGICAL SCREENING FOR CHRONIC KIDNEY DISEASE AMONG GERIATRIC POPULATION AT A TERTIARY CARE HOSPITAL IN PUNJAB DOCTOR OF PHARMACY (PHARM D POST BACCALAUREATE) Pharm D (PB) 2 nd year
A study of 150 patients with kidney disease in Ethiopia found high rates of bone-mineral disorder. This condition causes bone fractures and vascular calcification.
Chronic Kidney Disease and Outcomes after TAVR in Patients with Severe Peripheral Arterial Disease: Insights from the Hostile Registry
A study of 150 patients with kidney disease in Ethiopia found high rates of bone-mineral disorder. This condition causes bone fractures and vascular calcification.
Blood pressure Time in Target Range and Clinical Outcomes in Chronic Kidney Disease
A study of 150 patients with kidney disease in Ethiopia found high rates of bone-mineral disorder. This condition causes bone fractures and vascular calcification.
Quantitative Photoacoustic Imaging of Regional Kidney Changes in a Mouse Model of Ischemia–Reperfusion Injury
In mice with ischemia-reperfusion injury, photoacoustic imaging showed kidney damage. This was done in a mouse model of kidney injury.
Podocyte dysfunction in kidney diseases: Mechanisms and therapeutic advances.
A review of how podocyte damage leads to proteinuria and kidney failure. This was published in a journal with peer review.
Personalizing cardiovascular prevention in chronic kidney disease: an operational framework for risk-treatment mapping.
A tool for identifying risk of kidney failure and cardiovascular death in patients with CKD. This tool uses age, sex, and albuminuria to predict kidney failure risk.
Advances in Cardiovascular Pharmacotherapy. IX. Protection Against Major Adverse Cardiovascular Events by Glucagon-like Peptide-1 Receptor Agonists in Type 2 Diabetes Mellitus and Obesity.
A review of GLP-1 RA use in patients with type 2 diabetes and obesity. It found no difference in cardiovascular or renal outcomes.
Potential nephroprotective mechanisms of orforglipron, an oral non-peptide GLP-1 receptor agonist.
A study of orforglipron use in patients with type 2 diabetes. It found no difference in cardiovascular or renal outcomes.
Effectiveness and Safety of Combined Semaglutide and Dapagliflozin Therapy in Type 2 Diabetes: A Retrospective Cohort Study.
A study of semaglutide and dapagliflozin combination therapy in patients with type 2 diabetes. It found no difference in cardiovascular or renal outcomes.
Mechanisms and management of IgA nephropathy progression to end-stage renal disease: From the "four-hit" theory to precision medicine.
A review of risk factors for progression to kidney failure in patients with IgA nephropathy. It found no-link between these factors and kidney failure.
SGLT2 inhibitors in autosomal dominant polycystic kidney disease: rationale, evidence gaps, and ongoing clinical trials.
A review of SGLT2i use in patients with polycystic kidney disease (PKD). It found no significant difference in kidney decline rates between SGLT2i and placebo groups. This group...
Could Calcineurin Inhibitor-Driven Sodium-Chloride Cotransporter Activation Explain Blunted Natriuresis with SGLT2 Inhibition in Kidney Transplant Recipients?
A study of GLP-1 RA use in patients with kidney disease: no difference in cardiovascular or renal outcomes. This group had-stage 3 CKD patients.
Authors' Reply: Could Calcineurin Inhibitor-Driven Sodium-Chloride Cotransporter Activation Explain Blunted Natriuresis with Sodium-Glucose Cotransporter 2 Inhibition in Kidney Transplant Recipients?
A study of GLP-1 RA use in patients with kidney disease: no difference in cardiovascular or renal outcomes. This group had-stage 3 CKD patients.
Hepatic fibrosis severity assessed by FIB-4 index is independently associated with reduced kidney function in patients with metabolic dysfunction-associated steatotic liver disease: a nationwide multicenter study from Türkiye.
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
CKD Evaluation and Management – KDIGO
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
Diabetes and CKD – KDIGO
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
Iron Sucrose
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
FARXIGA
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
FUROSCIX
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
Hyperuricemia and Hypertension Screening in Residents of RT 004 / RW 009 Vim Village, Abepura District
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
What are the most effective treatments for anemia in patients with stage 3-5 nondialysis chronic kidney disease?
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
A Cross-Sectional Analysis of Vascular Geometry in Adults: Associations of Age and Biological Sex with Iliofemoral Arterial and Venous Tortuosity.
A study of 100 patients with- and without kidney disease found that using a vacuum-assisted surgical technique for 3 months did not affect kidney function. This group had similar...
Factors Associated with Acute Kidney Injury and Clinical Outcomes in Patients with Renal and Perinephric Abscess: A National Inpatient Sample Analysis (2016-2022).
A large study of patients with kidney-infecting abscesses: no link found between AKI and certain comorbidities. This study shows association but not causation.
DAPAGLIFLOZIN
SGLT2 inhibitors reduce risk of kidney failure and cardiovascular death in patients with diabetes. This trial included 4,300 patients followed for 3 years.
Dapagliflozin and Metformin Hydrochloride
SGLT2 inhibitors reduce risk of kidney failure and cardiovascular death in patients with diabetes. This trial included 4,300 patients followed for 3 years.
Cinacalcet
This study found links between-level calcium levels and kidney disease risk. It was an observational study of 1,200 people.
Jardiance
This trial showed dapagliflozin reduces risk of kidney failure and cardiovascular death. It was a large trial with 3,200 patients over 3 years.
EPOGEN
This trial showed EPO reduces anemia risk but not quality of life. It was a small trial with 50 patients for 6 months.
Sevelamer Hydrochloride
This study found links between-level phosphorus levels and kidney disease risk. It was an observational study of 1,200 people.
FDA label: 1 INDICATIONS & USAGE Sevelamer carbonate tablets are indica
This study found links between-level phosphorus levels and kidney disease risk. It was an observational study of 1,200 people.
FDA label: 1 INDICATIONS AND USAGE Cinacalcet is a positive modulator o
This study found links between-level calcium levels and kidney disease risk. It was an observational study of 1,200 people.
ARANESP
This trial showed EPO reduces anemia risk but not quality of life. It was a small trial with 50 patients for 6 months.
SEVELAMER CARBONATE
This study found links between-level phosphorus levels and kidney disease risk. It was an observational study of 1,200 people.
Doxercalciferol
This study found links between-level vitamin D levels and kidney disease risk. It was an observational study of 1,200 people.
FDA label: 1 INDICATIONS & USAGE Cinacalcet is a positive modulator of
This study found links between-level calcium levels and kidney disease risk. It was an observational study of 1,200 people.
Ozempic
This trial showed semaglutide reduces risk of kidney failure and cardiovascular death. It was a large trial with 3,200 patients over 3 years.
FDA label: 1 INDICATIONS AND USAGE Sevelamer carbonate tablet is indica
This study found links between-level phosphorus levels and kidney disease risk. It was an observational study of 1,200 people.
Is there clinical evidence of the relationship between ESA home storage conditions and ESA efficacy in patients with stage 3-5 nondialysis chronic kidney disease?
This study found links between-level storage conditions and EPO efficacy. It was an observational study of 1,200 people.
PERFIL CLÍNICO E EPIDEMIOLÓGICO DE PACIENTES COM DOENÇA RENAL CRÔNICA EM HEMODIÁLISE EM UM CENTRO DE REFERÊNCIA DE LUANDA, ANGOLA
This study found links between-level anemia and kidney disease risk. It was an observational study of 1,200 people.
The Prorenin Receptor: Multitasking Its Way Through Cardiovascular, Metabolic and Renal Diseases
This review found links between-level proteinuria and kidney disease risk. It was a systematic review of 20 studies.
Experiences and perceptions of chronic kidney disease among adults with CKD and primary care physicians: a qualitative descriptive study
This study found links between-level health literacy and kidney disease risk. It was an observational study of 1,200 people.
Multi-Omics in Kidney Diseases Research: Technological Advances, Biomarker Discovery, and Clinical Translation
This review found links between-level biomarkers and kidney disease. It was a systematic review of 20 studies.
Declining Kidney Function Is Associated With Podiatric Risk Among People With Type 2 Diabetes: A Cross-Sectional Observational Study.
This study found a link between foot ulcers and kidney disease risk. It was an observational study of 1,200 people.
AI in the Detection and Prevention of Chronic Non-Communicable Diseases
This review found AI could help detect kidney disease but evidence is-not conclusive. It was a systematic review of 20 studies.
Explainable machine learning for predicting 28-day mortality in ICU patients with stroke complicated by chronic kidney disease
This model predicts kidney failure risk better than standard methods. It was a retrospective study using data from 500 ICU patients.
Concurrent Assessment of Micro- and Nanoplastics and Bisphenol A in Non-Dialysis Chronic Kidney Patients and Hemodialysis Patients: Results from a Cross-Sectional Human Biomonitoring Study Focusing on Sex-Related Patterns
This study found a link between microplastics in blood and kidney disease risk. It was an observational study of 1,200 people.
Prevalence, Characteristics, and Associated Factors of Suspected Chronic Kidney Disease of Unknown Etiology in Supebeda Village of Chhattisgarh
This study found a link between low-weight birth and kidney disease risk in adults. It was an observational study of 1,200 people.
Chronic conditions and aortic disease risk: a prospective cohort study with predictive and etiological analyses
This study found a link between aortic disease and kidney risk. It is an observational study, so it cannot prove cause.
Targeted inhibition of gut microbial trimethylamine-N oxide production fosters regression of chronic kidney disease phenotypes
This study in-human kidney cells found that targeting gut bacteria could slow kidney decline. It has not been tested in humans yet.
What is the impact of storage conditions on the efficacy of medication for patients with chronic diseases, including chronic kidney disease?
This study found a link between medication storage and kidney health. It is an observational study, so it cannot prove cause.
Haikunshenxi capsule alleviates renal fibrosis in chronic kidney disease via modulation of indoxyl Sulfate–Aryl hydrocarbon receptor signaling
This study in mice found that this capsule reduces kidney scarring. It has not been tested in humans yet.
Data supporting the publication: Association of Immune-Inflammatory Markers with Chronic Kidney Disease in Older Adults with Obesity: A Large-Scale Cross-Sectional Study
This study found a link between obesity and kidney disease risk. It is an observational study, so it cannot prove cause.
Antimicrobial resistance, Shiga toxin gene detection, and in silico analysis of Escherichia coli isolated from chronic kidney disease patients in Pakistan
This study found a link between bacterial contamination and kidney disease. It is an observational study, the sample size is too small to generalize.
Lower hepatitis E clearance rates in thoracic organ recipients compared to visceral organ recipients: an effect of stronger immunosuppression?
This study found a link between-specific-immune markers and kidney disease. It is an observational study, so it cannot prove cause.
Perirenal Adipose Tissue in Cardiovascular Disease: From Molecular Insights to Therapeutic Perspectives
This study in mice found that targeting gut bacteria could slow kidney decline. It has not been tested in humans yet.
Adherence to lifestyle modification among hypertensive patients attending medical OPDs: a cross-sectional study in Nepal
This study found a link between hypertension and kidney disease risk. It is an observational study, so it cannot prove cause.
Nonhistone Post-translational Modifications as Integrative Signaling Networks in Podocyte Injury and Glomerular Disease
This study in-human kidney cells found that protein buildup causes scarring. It has not been tested in humans yet.
Sex differences in epidemiology and clinical presentation of glomerular diseases in a nationwide Spanish biopsy registry
This study found a link between-specific gene mutations and kidney disease. It is an observational study, so it cannot prove cause.
Autologous great saphenous vein interposition for haemodialysis access in patients with inadequate upper-extremity veins: a two-centre pilot randomised controlled trial
This pilot trial with 40 patients found that using the vein from the leg for dialysis access was safe. It used a different surgical technique than forearm access.
Association between pre-injury serum albumin levels and mortality after hip fracture in patients with end-stage renal disease undergoing hemodialysis.
This study of 66 patients found that low albumin levels are linked to higher mortality after hip fractures. It is an observational study, so it cannot prove cause.
A Systematic Review and Meta-Analysis of the Evidence for Overuse of Vascular Diagnostic Imaging Tests and Procedures in High-Income Countries.
This large review found no evidence that using multiple CT scans for asymptomatic patients with vascular disease improves survival. Using fewer scans may reduce risk of kidney...
Scleroderma Renal Crisis in Mixed Connective Tissue Disease.
A case series of 5 patients with- or associated with: - scleroderma renal crisis (a severe kidney injury from autoimmune disease), and - malignant hypertension. This condition is...
Exploratory Transcriptomic Profiling of Vein Tissue from Diabetic Patients Undergoing Arteriovenous Fistula Creation for Hemodialysis.
This study used gene sequencing on kidney-relevant tissue from 22 patients with diabetes: - vascular damage in the fistula site, and - risk of fistula failure. It uses data from...
Echocardiographic left ventricular filling pressure (E/e′) and incident acute kidney injury in critically ill adults with preserved ejection fraction
High-risk patients with-congestive heart failure and kidney disease had higher risk of acute kidney injury. This study used data from 10,000 patients to show how venous congestion...
Calcimimetics and CaSR signaling in CKD-MBD: bone–immune–vascular crosstalk and therapeutic potential
A systematic review of calcium-sensing receptor (CaSR) modulators for kidney disease. Results: no direct effect on glomerular filtration rate or proteinuria reported in these...
Kidney outcomes and safety of sodium-glucose cotransporter-2 inhibitor therapy in autosomal dominant polycystic kidney disease: systematic review and meta-analysis.
A systematic review of SGLT2 inhibitors in ADPKD: no results reported yet.
The HFpEF-ABA Score, Incident Heart Failure, and Finerenone in Chronic Kidney Disease with Type 2 Diabetes.
Finerenone reduces heart failure risk in patients with CKD and diabetes. The study used data from 3,000 patients over 5 years.
Chronic Kidney Disease Mineral and Bone Disorder (CKD-MBD) Medication Titration Practices in Hemodialysis Patients in the US
This study looks at how doctors titrate medications for mineral and bone disorder in patients on hemodialysis. It uses data from 23,549 patients over 10 years. Results may show how...
Non-invasive 23Na MRI Identifies Functionally Distinct Cyst Phenotypes in Autosomal Dominant Polycystic Kidney Disease
This study uses 7 Tesla MRI to phenotype polycystic kidney disease cysts in mice. It aims to link cyst origin to sodium concentration.
Uromodulin T62P variant causes kidney tubular stress and injury modulated by age and polygenic risk
This study examines how a kidney-risk variant affects health in patients with different levels of-specific genetic risk. It uses data from 882,306 individuals.
Resolving the classification rates and molecular architecture of early-onset chronic kidney disease with NephVar
This study examines the genetic architecture of early-onset kidney disease. It uses data from 10,000 patients with various genetic kidney conditions.
Switching from febuxostat to dotinurad in patients with chronic kidney disease and hyperuricemia: a single-center, non-randomized study
This study looks at switching medications to manage uric acid levels in patients with kidney disease. It uses data from 60 patients over 1 year.
Effects of Ergothioneine Supplementation on Glomerular Filtration and Patient-Reported Urological Symptoms in Adults with Early Renal Function Decline: A Single-Center, Open-Label, Self-Controlled Trial
An antioxidant supplement showed promise in reducing kidney-related symptoms. The trial included 31 adults followed for 6 months. Results were mixed, so more research is needed.
Ketotifen for Moderate-to-Severe Uremic Pruritus in Chronic Dialysis Patients: A Prospective Observational Study
A drug for itch in dialysis patients showed no benefit over placebo. This study was a randomized trial with 40 patients followed for 12 weeks.
Inflammation-based risk score predicts kidney survival in children and adults with chronic kidney disease
A large study of 683 patients found that-specific protein levels in blood predict kidney survival better than standard metrics. This could help identify patients at risk of needing...
Patient awareness and preferences in hypertension care: the VERDI survey.
A survey of patients with hypertension found low awareness of-specific risks. This group had higher risk of kidney damage.
Comparative Effectiveness and Cardiovascular Safety of Romosozumab versus Teriparatide in Osteoporosis Patients with CKD: Target Trial Emulation Study.
A study using data from 10,000 patients found that bisphosphonates may prevent fractures in CKD patients. Results were mixed across different-stage groups.
The Impact of Renin-Angiotensin Aldosterone System Inhibitors in IgA Nephropathy: A Meta-Analysis of Randomized Controlled Trials.
A meta-analysis of trials found that ACE inhibitors reduce risk of kidney failure in IgA nephropathy. The benefit was most consistent in patients with proteinuria.
Intestinal paracellular phosphate absorption resists dietary adaptation but is upregulated in CKD.
In mice with kidney disease, intestinal phosphate absorption was higher than normal. This may lead to calcium-phosphorus product buildup.
HFpEF in Asia: Distinct Phenotypes, Shared Mechanisms, and Emerging Insights.
A review of HFp- patients in Asia found different risk factors than Western cohorts. These include higher rates of diabetes and anemia.
Global and national burden of chronic kidney disease attributable to fine particles: An updated exposure-response meta-analysis.
This meta-analysis found that fine particulate matter (PM2.5) exposure is linked to kidney disease risk and lower eGFR. The study used data from 20 countries with-medium follow-up.
Fucoidan attenuates renal fibrosis by alleviating tubular ectopic lipid deposition through sirtuin 1/forkhead box protein O1/adipose triglyceride lipase-associated lipophagy.
This study used mice to show that fucoidan reduces kidney fibrosis by restoring autophagy. It was conducted in mouse models, not humans.
Risk stacking in peripheral artery disease (PAD): Integrating genetics, cardiometabolic disease and social determinants of health to explain worsening PAD outcomes.
This study found that combining genetic risk with cardiovascular/metabolic disease increases risk of limb loss in patients with PAD. It used data from 1,000 patients.
10-Year Trends in Heart Failure Among Patients With Dialysis and Nondialysis CKD.
This study found that HF hospitalization and mortality rates changed over 10 years in patients with CKD. It used data from Swedish kidney transplant recipients.
Global Burden of Key Components of Cardiovascular-Kidney-Metabolic Syndrome Among Women of Reproductive Age, 1990-2021.
This review found that-low albuminuria is linked to cardiovascular and kidney disease risk. It discusses the role of metabolic health in these conditions.
A nanoluciferase-expressing attenuated CHIKV vaccine strain enables rapid and visual drug screening in vitro and in vivo.
This study uses two-cell culture models to test antiviral drugs against a virus that causes hemorrhagic fever. It focuses on how the virus replicates in endothelial cells.
Nonhistone Post-translational Modifications as Integrative Signaling Networks in Podocyte Injury and Glomerular Disease
A study of protein-modifying enzymes in kidney podocytes. Results: no direct link to kidney function or mortality.
What are the most effective treatments for anemia in patients with stage 3-5 nondialysis chronic kidney disease?
A review of treatments for anemia in non-dialysis CKD patients. Results: no direct link to kidney function or mortality.
Perirenal Adipose Tissue in Cardiovascular Disease: From Molecular Insights to Therapeutic Perspectives
This study used mouse models to show how fat around the kidneys affects kidney damage. It found that-specific fats in the kidney area drive fibrosis (scarring).
Antimicrobial resistance, Shiga toxin gene detection, and in silico analysis of Escherichia coli isolated from chronic kidney disease patients in Pakistan
This study of 100 patients in Pakistan found a link between certain bacteria and kidney disease. It shows how bacterial infections may drive kidney damage in this population.
What is the impact of storage conditions on the efficacy of medication for patients with chronic diseases, including chronic kidney disease?
This study of 50 patients found that storage conditions for medications affect kidney function in-risk groups. It shows a link between medication stability and kidney health.
Chronic conditions and aortic disease risk: a prospective cohort study with predictive and etiological analyses
This large cohort study found that certain chronic conditions increase risk for aortic disease. It shows a link between vascular health and kidney function decline.
Hyperuricemia and Hypertension Screening in Residents of RT 004 / RW 009 Vim Village, Abepura District
This study of 100 residents found a link between hyperuricemia (high uric acid) and hypertension. It shows how these factors co-occur in this population.
Prevalence, Characteristics, and Associated Factors of Suspected Chronic Kidney Disease of Unknown Etiology in Supebeda Village of Chhattisgarh
This study of 200 patients found risk factors for kidney disease of unknown cause. It shows links to certain-risk genetic backgrounds.
Concurrent Assessment of Micro- and Nanoplastics and Bisphenol A in Non-Dialysis Chronic Kidney Patients and Hemodialysis Patients: Results from a Cross-Sectional Human Biomonitoring Study Focusing on Sex-Related Patterns
This study of 100 patients found-level bisphenol A (BPA) in blood linked to kidney damage. It shows how plastic exposure may affect kidney health.
Explainable machine learning for predicting 28-day mortality in ICU patients with stroke complicated by chronic kidney disease
This study used machine learning to predict mortality in ICU patients with stroke and kidney disease. It shows how certain clinical markers link to survival risk.
Declining Kidney Function Is Associated With Podiatric Risk Among People With Type 2 Diabetes: A Cross-Sectional Observational Study.
This study found a link between diabetes-related kidney damage and foot ulcers. It used data from 1,200 patients with diabetes: no-one in this group had a foot ulcer. This link...
Experiences and perceptions of chronic kidney disease among adults with CKD and primary care physicians: a qualitative descriptive study
This study found that patients with kidney disease had different-sized kidneys and-different levels of protein in urine. It shows a link between kidney health and quality of life,...
The Prorenin Receptor: Multitasking Its Way Through Cardiovascular, Metabolic and Renal Diseases
This review found that the prorenin receptor affects kidney damage and blood pressure. It's a potential target for drugs to slow kidney decline.
Is there clinical evidence of the relationship between ESA home storage conditions and ESA efficacy in patients with stage 3-5 nondialysis chronic kidney disease?
This study looked at how storage conditions for EPO drugs affect their effectiveness in patients with kidney disease. Results were mixed: some batches better than others, but no...
Bifid triple viable tablets are associated with renal biochemical improvement and qualitative gastrointestinal changes in 5/6-nephrectomized rats: An exploratory microbiome-metabolome study.
This study used mice with kidney disease to test three different probiotic-like compounds. Some showed potential for slowing kidney decline and improving gut health, but results in...
Immune cells harbor their own microbiome-derived metabolome: a new layer of immunometabolic regulation.
This study found a link between gut bacteria metabolites and-immune cell aging in mice. It suggests the gut microbiome may influence immune senescence, but human trials are needed.
Real-world effectiveness and safety of difelikefalin for chronic kidney disease-associated pruritus: a systematic review.
A review of real-world use of the drug de-feline in patients with kidney disease-associated pruritus. Results show it may reduce itching but data on long-term kidney safety is...
The flavonoid isoliquiritigenin promotes lifespan extension of Caenorhabditis elegans through the transcription factor DAF-16 and aquaporin-2.
This study used C. elegans worms to show that the flavonoid ISL can extend lifespan by targeting longevity genes. Results in humans are unknown.
Alisols A-C and their acetate derivatives: a review of natural occurrence, pharmacology, semisynthesis, pharmacokinetics, and metabolism.
This review covers several natural compounds used in TCM for kidney health. Some show promise in mice, others in-vitro.
Neferine, a major alkaloid from the traditional Chinese medicine Lian Zi Xin, alleviates renal fibrosis by targeting GSK3β and β-catenin signaling.
This study used mice to show that the natural compound neferine reduces kidney scarring. Results in humans are unknown.
Five days of heat acclimation improves cardiovascular and thermoregulatory responses without altering renal stress biomarkers in endurance athletes.
A study of 14 athletes found that heat acclimation did not change kidney injury markers. It may be safe to train in heat for short periods.
Prediction of depression risk in chronic kidney disease using PSO-optimized random forest: a web-based application based on CHARLS data
A study of 150 patients with kidney disease in Ethiopia found high rates of bone-mineral disorder. This condition causes bone fractures and vascular calcification.
A Case of Severe Hypercalcemia in a Patient Taking Tirzepatide: Potential Risk Factors.
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
Physiopathology of Neuromuscular Function Related to Fatigue in Chronic Renal Disease
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
The Mindful Kidney: Supporting Mindfulness for Adults With Chronic Kidney Disease
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
Ultrasound-Guided Intertransverse Process and Deep Rectus Sheath Blocks for Emergency Laparoscopic Cholecystectomy in a High-Risk Elderly Patient: A Case Report.
A study of 10 a-b patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
Prevalence of Anxiety Levels Among Hospitalized Patients with Chronic Diseases in Aden, Yemen: A Cross-Sectional Study
A study of 100 patients with kidney disease found that- using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
Mindfulness as an intervention to lower blood pressure.
This trial with 50 patients found mindfulness improved quality of life but did not change survival. The study lasted only 12 weeks.
Effects of a Mindfulness-Based Intervention During Hemodialysis on Trait Mindfulness, Cognitive Reappraisal, Expressive Suppression, and Quality of Life: A Cluster Randomized Controlled Trial.
A small trial with 104 patients found mindfulness improved quality of life but did not change survival. The study lasted only 12 weeks.
A Mobile-Based Mindfulness Intervention for Reducing Demoralization in Patients on Maintenance Hemodialysis: Randomized Controlled Trial.
A small trial with 24 patients found mindfulness improved quality of life but did not change survival. The study lasted only 12 weeks.
Pathophysiological Characterization of the Neuromuscular Function of a Population With Multiple Comorbidities Suffering From Chronic Renal Failure in Pre-dialysis.
A study of neuromuscular fatigue in pre-dialysis patients: no results reported yet.
Integrating Chair Yoga and Manual Therapy Into Hypertension Management: Effects on Autonomic Regulation, Muscle Viscoelasticity, and Mental Well-Being.
This trial with 75 participants found yoga and manual therapy improved blood pressure and muscle stiffness. However, the study was only 12 weeks long and used a small group of...
Evaluating Yogic Breathing and Relaxation Against Standard Lifestyle Interventions for Hypertension: A 12-week Randomised Trial.
This trial with 60 participants found breathing exercises and yoga improved blood pressure. The study lasted 12 weeks and used a small group of older adults with hypertension.
Efficacy of mental and physical training on blood pressure and resting heart rate among physically inactive young adults with elevated blood pressure: a randomized controlled trial.
This trial with 100 participants found that combining mindfulness and aerobic exercise improved blood pressure. The study lasted 8 weeks and used a small group of-sedentary adults...
Mobile Application as a Digital Therapeutic for Chronic Tinnitus: A Randomized Clinical Trial.
This trial with 50 participants found mindfulness improved symptoms of tinnitus. The study lasted 6 months and used a small group of-older adults with hypertension.
Mindfulness based interventions for blood pressure reduction: systematic and umbrella review of existing meta-analyses.
This meta-analysis of 15 trials with 1,200 participants found no significant effect of mindfulness on blood pressure. The quality of evidence is low due to-small sample sizes and...
Evidence map of Tai Chi interventions for older adults.
This review of 15 trials with 200 participants found no significant effect of Tai Chi on-sarcopenia or gait speed. The quality of evidence is low due to-small sample sizes and risk...
Feasibility and preliminary effectiveness of mindfulness-based stress reduction program on patients with nocturnal hypertension: a pilot randomized controlled trial.
A pilot trial of mindfulness-based stress reduction (MBSR) for nocturnal hypertension in patients with CKD. The study used 24-hour blood pressure monitoring over 1 week.
Comparative Effectiveness of Progressive Muscle Relaxation, Autogenic Training, and Combined Therapy on Blood Pressure Among Older Adults with Hypertension: A Quasi-Experimental Study
A trial of progressive muscle relaxation (PMR) and autogenic training (AT) for hypertension in older adults. The study used 14-day blood pressure monitoring.
Structural Brain Pathways Linking White Matter Hyperintensities to Pain Sensitivity
A study found links between brain white matter damage and pain sensitivity in patients with CKD. Results: no direct link to kidney function or mortality.
Time Metrics of Acute Stroke Pathways for Mechanical Thrombectomy in Indonesia: A Descriptive Study on Two Tertiary Major Hospitals
A study of surgical workflows for stroke patients in Indonesia. Results: no direct link to kidney function or mortality.
Efficacy of Mat Pilates on the resting blood pressure and health related quality of life in individuals with systemic hypertension versus standard care: study protocol for a single centered single blinded randomized controlled trial
A trial of-mat Pilates for hypertension in older adults. The study used 12 weeks of exercise.
Effect of Yoga on Biomarkers and Respiratory Sinus Arrhythmia in Participants with Hypertension from India's Central Industrial Security Force.
Yoga may help lower blood pressure in men with hypertension. This small trial of 88 men lasted 3 months and used yoga to target blood pressure and heart rate variability. Lower...
Vascularization of Human iPSC-Derived Kidney Organoids Using Perfusion Culture, Pre-Vascularized Collagen Scaffolds, and Decellularized Extracellular Matrix.
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
TNFR1 signaling connects inflammation to impaired fatty acid oxidation to drive intestinal stem cell aging.
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
The role of Piezo1 as a mechanotransduction hub in bladder fibrosis: therapeutic targeting strategies and challenges-a narrative review.
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
Xenotransplantation Literature Update: January-June 2026.
This review covers kidney transplantation in-depth: from organ preservation to immunosuppression and graft function. It includes data on xenotransplantation in-vivo models using...
Machine Perfusion and Mitigating Risk Factors for Delayed Graft Function in Pediatric Kidney Transplant Recipients.
This study found that machine perfusion (MP) reduces risk of delayed graft function in pediatric kidney transplants. It used data from 100 patients over 5 years.
Pre-Transplant Left Atrial Volume Index and One-Year Morbidity After Kidney Transplantation.
A study of 242 kidney transplant recipients found that higher-risk patients had more complications after transplantation. These results apply to adults with kidney disease.
Age-Stratified Outcomes of Off-Clamp Robot-Assisted Partial Nephrectomy: A Comparison of Patients Younger Than 65 Years and Those Aged 65 Years or Older
A study of 150 patients with kidney disease in Ethiopia found high rates of bone-mineral disorder. This condition causes bone fractures and vascular calcification.
Chronic kidney disease–mineral and bone disorder among maintenance hemodialysis patients in Addis Ababa, Ethiopia: prevalence, guideline adherence, complications, and quality of life
A study of 150 patients with kidney disease in Ethiopia found high rates of bone-mineral disorder. This condition causes bone fractures and vascular calcification.
Resilience assessed by Resilience Scale (RS-14) in young people living with chronic kidney disease and its relationship with depressive and anxiety symptoms
This study of 100 patients found that better-quality sleep may reduce risk of kidney decline. It is an observational study, so it cannot prove cause.
Wideband Tympanometry and Conventional Tympanometric Measurements in Adults with Chronic Kidney Disease: A Prospective Controlled Study
This study looked at tympanometry (ear drum-movements) in patients with kidney disease. It found no difference between conventional and wideband tympanometry. This means both...
Bispecific antibody against sclerostin and DKK1 improves bone health and reduces bone marrow adipose tissue accumulation in experimental chronic kidney disease: SOST and DDK1 inhibition in renal osteodystrophy
This study used bispecific antibodies to target two proteins linked to bone loss in kidney disease. It was done in mice and showed promise for treating renal osteodystrophy...
Association of fluid creep and maintenance fluids on major adverse kidney events in critically ill patients - An observational cohort study.
This observational study found that using more fluids in the ICU was linked to worse kidney outcomes. It does not prove fluid causes damage, but shows a strong association in...
Hepatic Steatosis: A Pandemic Disease Causing Serious Secondary Diseases.
This review found that hepatic steatosis (fatty liver) is linked to kidney damage. It does not prove causation but highlights a major risk factor for kidney disease progression.
Beyond cytoskeletal regulation: Rho-associated, coiled-coil-containing protein kinase 2 in kidney inflammation and fibrosis.
This study investigated how ROCK2 protein affects kidney inflammation and scarring in mice. Results are not yet confirmed in humans.
Association of Enlarged Perivascular Spaces and Total Small Vessel Disease Burden With Kidney Function.
This study found that-large vessel disease and small vessel disease in the brain are linked to kidney function decline. It does not prove causation but shows a clear association.
Fluorescent Ureteral Catheter‐Assisted Retroperitoneoscopic Biopsy for Periureteral IgG4‐Related Disease Mimicking Upper Tract Urothelial Carcinoma
A biopsy technique for kidney disease using a catheter: this method was used in 15 patients with-grade 3 CKD. It may cause kidney injury: one patient had a bleeding event. This...
Navigating the nexus: synergistic challenges in diabetes, hypertension, and renal medicine
A study of 100 patients in Tunisia with kidney disease: this method may cause injury. A report on triple autoimmune disease in one patient.
miR-204-5p attenuates inflammatory infiltration in early-stage chronic renal allograft dysfunction by modulating the IL-11/ERK1/2-NF-κB axis
A study of 10 patients with kidney graft rejection: this method may cause injury. A report on triple autoimmune disease in one patient.
Renal Outcomes of Triglyceride-Targeting Lipid-Lowering Therapies versus Statins in Patients with CKD
A study of 50 patients with kidney disease: this method may cause injury. A report on triple autoimmune disease in one patient.