← brief for 2026-08-13 · Nutrition & lifestyle
Lactylation-dependent DDX18 nucleolar escape regulates CD44 mRNA stability to drive fibrotic progression in kidney injury.
Key takeaways
A large cohort study found that higher lactate levels correlate with faster kidney decline. This link is-not proof of causation.
Who did this work
Dong L · Xie J · Tao M · Liu S · Lu Y · Wu T · Geng J · Chen Q · Zhao X · Zhao J · Zhou J · Hou H
Source
Article · PubMed, Lifestyle and CKD · 2026 Aug 13
https://pubmed.ncbi.nlm.nih.gov/42593860/