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Real-world effectiveness and safety of difelikefalin for chronic kidney disease-associated pruritus: a systematic review.

Article B Peer reviewed Small trial

Key takeaways

A review of real-world use of the drug de-feline in patients with kidney disease-associated pruritus. Results show it may reduce itching but data on long-term kidney safety is limited.

Who did this work

Sheldon R · Wadodkar M · Gan A · Chien HY · Baharani J

Source

Article · PubMed, Lifestyle and CKD · 2026 Aug 11
https://pubmed.ncbi.nlm.nih.gov/42576770/