← brief for 2026-08-13 · Nutrition & lifestyle
Neferine, a major alkaloid from the traditional Chinese medicine Lian Zi Xin, alleviates renal fibrosis by targeting GSK3β and β-catenin signaling.
Key takeaways
This study used mice to show that the natural compound neferine reduces kidney scarring. Results in humans are unknown.
Who did this work
Li J · Qin Y · Yu Z · Chen P · Huang X · Zhu Z · Fang X · Liu Z · Wu S
Source
Article · PubMed, Climate, heat and the kidney · 2026 Aug 11
https://pubmed.ncbi.nlm.nih.gov/42580543/