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Genkwanin mitigates renal fibrosis by reprogramming profibrotic signaling and restoring TFEB-mediated autophagy

Paper D Peer reviewed Preclinical

Key takeaways

This study used-cell models to show how genkwanin reduces kidney scarring (fibrosis). It works by fixing protein recycling in cells, but results in humans are not yet known.

Who did this work

Shen Wang (Tongji University) · Yu He (Tongji University) · Xin Gan (Tongji Hospital) · Hao Kang (Tongji Hospital) · Zhu Zhou (Kunming Medical University) · Zonghai He (Kunming Medical University)

Source

Paper · OpenAlex, CKD works · 2026-08-13
https://doi.org/10.3389/fphar.2026.1861855