← brief for 2026-08-14 · Slowing decline

Metabolic Burden and Hyperuricemia Are Associated With CKD-Related Outcomes in Individuals With and Without Steatotic Liver Disease.

Article A Peer reviewed Meta-analysis or large trial

Key takeaways

In a large Japanese cohort of 107,000 people with and without fatty liver disease, kidney decline was linked to both fat in the liver and metabolic factors like diabetes. This means managing weight and blood sugar is crucial for kidney health, even without fatty liver.

Who did this work

Iwaki M · Fujii H · Kamada Y · Suzuki Y · Sawada K · Tatsuta M · Maeshiro T · Tobita H · Tsutsumi T · Akahane T · Hasebe C · Kawanaka M

Source

Article · PubMed, CKD progression and prevention · 2026 Aug 14
https://pubmed.ncbi.nlm.nih.gov/42598891/