← brief for 2026-08-18 · People & money

Cellular crosstalk between endothelial and vascular smooth muscle cells via the BACH1/COL3A1 axis promotes vascular calcification in chronic kidney disease

Paper D Peer reviewed Preclinical

Key takeaways

This study in mouse models found that the BACH1/COL3A1 axis drives vascular calcification in CKD patients. It shows how endothelial and smooth muscle cells interact to cause vessel hardening.

Who did this work

Jing Ning · Sitian Fang · Minzi Qiu · Honghong Zou · Yanxia Chen

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-08-18
https://doi.org/10.1007/s00011-026-02339-x