← brief for 2026-08-18 · Slowing decline

Fructose directly remodels the translocase of the outer membrane to impair oxidative phosphorylation in podocytes

Paper D Peer reviewed Preclinical

Key takeaways

Fructose exposure in kidney cells caused mitochondrial damage. This was a cell-based study, so results may not translate to humans.

Who did this work

Wenyuan Wu (Nanjing University of Chinese Medicine) · Wenhe Wang (Center for Life Sciences) · Jingzi Zhang (Nanjing University of Chinese Medicine) · Qiongdan Liang (Nanjing University of Chinese Medicine) · Nannan Wang (Nanjing Medical University) · Li Chen (Nanjing University of Chinese Medicine) · Chengzhi Wang (Nanjing Medical University) · Jiahuang Li (Nanjing University of Chinese Medicine) · Yiyang Cong (Nanjing Medical University) · Hao Hong (Nanjing Medical University) · Xu Cheng (Nanjing University) · Maojun Yang (Southern University of Science and Technology)

Source

Paper · OpenAlex, CKD works · 2026-08-17
https://doi.org/10.1038/s41392-026-02896-x