← brief for 2026-08-20 · Slowing decline

Association of total and brain-derived Alzheimer's disease plasma biomarkers with brain amyloid deposition in a community-based sample.

Article B Peer reviewed Small trial

Key takeaways

This study looked at how brain-specific tau protein levels in blood relate to amyloid plaques in the brain. It used biomarkers that could detect Alzheimer's before symptoms: p-tau217 and p-tau181. Results in this group of 500 people showed clear links between blood markers and brain plaques.

Who did this work

Akinci M · Aziz F · Guzman D · Cheung L · Kong JX · Silver S · Eimicke J · Simoes S · Teresi JA · Brickman AM · Lao P · Luchsinger JA

Source

Article · PubMed, CKD severity and reversal · 2026 Jul 31
https://pubmed.ncbi.nlm.nih.gov/42620201/