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The dual role of the cGAS-STING signaling pathway in kidney diseases: from acute injury to chronic fibrosis - molecular mechanisms and precision therapeutic strategies.

Article B Peer reviewed Small trial

Key takeaways

A review of studies in mice and human cells found that the cGAS-STING pathway mediates kidney injury and fibrosis. This review covers multiple conditions including lupus nephritis.

Who did this work

Qi G · Xue F · Sun H · Yao X · Liu Q

Source

Article · PubMed, the drug frontier · 2026 Aug 5
https://pubmed.ncbi.nlm.nih.gov/42621049/